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Index > Protein center > Vmp1(Gene name) > Mouse
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  • Vmp1 (Gene name),
  • Vacuole membrane protein 1 (Protein name ),  VMP1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Vmp1(Tmem49);
    Protein name:
    Vacuole membrane protein 1;
    Alternative:
    Transmembrane protein 49;NF-E2-inducible protein 2(Protein ni-2);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with BECN1. Interacts with TJP1.
    Function:
    Stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis. Involved in cell-cell adhesion. Plays an essential role in formation of cell junctions (By similarity). Plays a role in the initial stages of the autophagic process through its interaction with BECN1.
    Subcellular Location:
    Endoplasmic reticulum-Golgi intermediate compartment membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein Vacuole membrane Multi-pass membrane protein Endoplasmic reticulum
    Protein Attributes:
    Sequence length:
    406
    Sequence:
    50:
    MAENGKNCDQ | RRIAMSKDQH | NGSLTDPSSV | HEKKRRDREE | RQNIVLWRQP | 
    100:
    LITLQYFSLE | TLVVLKEWTS | KLWHRQSIVV | SFLLLLAALV | ATYYVEGAHQ | 
    150:
    QYVQRIEKQF | LLYAYWIGLG | ILSSVGLGTG | LHTFLLYLGP | HIASVTLAAY | 
    200:
    ECNSVNFPEP | PYPDQIICPE | EEGAEGAISL | WSIISKVRIE | ACMWGIGTAI | 
    250:
    GELPPYFMAR | AARLSGAEPD | DEEYQEFEEM | LEHAEAAQDF | ASRAKLAVQK | 
    300:
    LVQKVGFFGI | LACASIPNPL | FDLAGITCGH | FLVPFWTFFG | ATLIGKAIIK | 
    350:
    MHIQKIFVIV | TFSKHIVEQM | VTFIGAVPGI | GPSLQKPFQE | YLEAQRQKLH | 
    400:
    HRSEAGTPQG | ENWLSWMFEK | LVVAMVCYFV | LSIINSMAQN | YAKRIQQRLN | 
    406:
    SEEKTK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Vacuole membrane protein 1
    Cat.:
    E14852b
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse Vacuole membrane protein 1
    Cat.:
    E14852m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse Vacuole membrane protein 1
    Cat.:
    E14852r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse Vacuole membrane protein 1
    Cat.:
    E14852h
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    MSDS:
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    Packing:
    96T
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    CLIA Kit for Mouse Vacuole membrane protein 1
    Cat.:
    U14852b
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Vacuole membrane protein 1
    Cat.:
    U14852m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Vacuole membrane protein 1
    Cat.:
    U14852r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Vacuole membrane protein 1
    Cat.:
    U14852h
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Mouse Vacuole membrane protein 1
    Cat.:
    P14852Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Vacuole membrane protein 1
    Cat.:
    P14852Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Vacuole membrane protein 1
    Cat.:
    P14852Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Vacuole membrane protein 1
    Monoclonal Antibody for Mouse Vacuole membrane protein 1
    Monoclonal Antibody for Mouse Vacuole membrane protein 1
    Monoclonal Antibody for Mouse Vacuole membrane protein 1
    Monoclonal Antibody for Mouse Vacuole membrane protein 1
    Protein for Mouse Vacuole membrane protein 1
    Protein for Mouse Vacuole membrane protein 1
    Protein for Mouse Vacuole membrane protein 1
    Protein for Mouse Vacuole membrane protein 1

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    References
    1. 1.
      "A novel lipopolysaccharide-inducible gene (#25)."
      Yamazaki S. , Muta T. , Takeshige K.
      Submitted (2000-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: C57BL/6.
      tissue: Spleen.
    2. 2.
      "NF-E2 induceble novel gene."
      Nagata Y. , Oda M. , Haruta H. , Todokoro K.
      Submitted (2001-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Cerebellum.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Czech II.
      tissue: Mammary tumor.
    6. 6.
      "The pancreatitis-induced vacuole membrane protein 1 triggers autophagy in mammalian cells."
      Ropolo A. , Grasso D. , Pardo R. , Sacchetti M.L. , Archange C. , Lo Re A. , Seux M. , Nowak J. , Gonzalez C.D. , Iovanna J.L. , Vaccaro M.I.
      J. Biol. Chem.282:37124-37133(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
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