Protein name:
Vacuole membrane protein 1 ;
Alternative:
Transmembrane protein 49 ;NF-E2-inducible protein 2 (Protein ni-2) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with BECN1. Interacts with TJP1.
Function:
Stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis. Involved in cell-cell adhesion. Plays an essential role in formation of cell junctions (By similarity). Plays a role in the initial stages of the autophagic process through its interaction with BECN1.
Subcellular Location:
Endoplasmic reticulum-Golgi intermediate compartment membrane
Multi-pass membrane protein
Cell membrane
Multi-pass membrane protein
Vacuole membrane
Multi-pass membrane protein
Endoplasmic reticulum
Protein Attributes:
50:
MAENGKNCDQ | RRIAMSKDQH | NGSLTDPSSV | HEKKRRDREE | RQNIVLWRQP |
100:
LITLQYFSLE | TLVVLKEWTS | KLWHRQSIVV | SFLLLLAALV | ATYYVEGAHQ |
150:
QYVQRIEKQF | LLYAYWIGLG | ILSSVGLGTG | LHTFLLYLGP | HIASVTLAAY |
200:
ECNSVNFPEP | PYPDQIICPE | EEGAEGAISL | WSIISKVRIE | ACMWGIGTAI |
250:
GELPPYFMAR | AARLSGAEPD | DEEYQEFEEM | LEHAEAAQDF | ASRAKLAVQK |
300:
LVQKVGFFGI | LACASIPNPL | FDLAGITCGH | FLVPFWTFFG | ATLIGKAIIK |
350:
MHIQKIFVIV | TFSKHIVEQM | VTFIGAVPGI | GPSLQKPFQE | YLEAQRQKLH |
400:
HRSEAGTPQG | ENWLSWMFEK | LVVAMVCYFV | LSIINSMAQN | YAKRIQQRLN |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Mouse
Rat
Human
ELISA Kit for Mouse Vacuole membrane protein 1
ELISA Kit for Mouse Vacuole membrane protein 1
ELISA Kit for Mouse Vacuole membrane protein 1
ELISA Kit for Mouse Vacuole membrane protein 1
CLIA Kit for Mouse Vacuole membrane protein 1
CLIA Kit for Mouse Vacuole membrane protein 1
CLIA Kit for Mouse Vacuole membrane protein 1
CLIA Kit for Mouse Vacuole membrane protein 1
Polyclonal Antibody for Mouse Vacuole membrane protein 1
Polyclonal Antibody for Mouse Vacuole membrane protein 1
Polyclonal Antibody for Mouse Vacuole membrane protein 1
Polyclonal Antibody for Mouse Vacuole membrane protein 1
Monoclonal Antibody for Mouse Vacuole membrane protein 1
Monoclonal Antibody for Mouse Vacuole membrane protein 1
Monoclonal Antibody for Mouse Vacuole membrane protein 1
Monoclonal Antibody for Mouse Vacuole membrane protein 1
Protein for Mouse Vacuole membrane protein 1
Protein for Mouse Vacuole membrane protein 1
Protein for Mouse Vacuole membrane protein 1
Protein for Mouse Vacuole membrane protein 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
C57BL/6 .
tissue :
Spleen .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
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[
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Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
tissue :
Cerebellum .
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PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
Czech II .
tissue :
Mammary tumor .
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"The pancreatitis-induced vacuole membrane protein 1 triggers autophagy in mammalian cells."
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION